Objective To investigate the cognition,attitude and practice of pediatric ICU nurses on daily sedation interruption（DSI）,and to provide references for clinical training. Methods Convenience sampling was used to conduct a questionnaire survey among 298 pediatric ICU nurses in 7 tertiary A children hospitals in China in July 2021. The general information questionnaire,questionnaires of knowledge,attitude,and behavior on DSI were self-designed. Results In terms of the cognition of 298 pediatric nurses on DSI,their knowledge score was 4（2,4） out of 10,and a total of 157 nurses（52.68%） said they did not know well or had never heard of DSI. In terms of attitude,their recognition score was 32（27,34） out of 40,and 217 nurses（72.82%） were willing to implement DSI,and 258 nurses（86.58%） wanted systematic training. In practice of nurses,221（74.16%） have not received relevant training,and 159 nurses（53.35%） never or rarely performed DSI. Conclusion Pediatric ICU nurses have a poor grasp of knowledge on DSI,while their recognition toward DSI is high. Their practice needs to be strengthened. Nursing managers should pay full attention to the training needs of pediatric ICU nurses and carry out systematic training on DSI basic knowledge and practical skills,so as to improve DSI practice level of nurses.

Objective To construct a risk prediction model for central venous catheter-associated deep venous thrombosis（CADVT） in children with congenital heart disease after surgery,and to verify the prediction effect of the model. Methods A total of 234 children hospitalized in the cardiac care unit of a tertiary first-class pediatric hospital in Zhejiang Province from January to November 2021 were conveniently selected as the model building subjects. According to whether CADVT occurred,they were divided into a CADVT group（53 cases） and a non-CADVT group（181 cases）. Logistic regression analysis was used to establish the risk prediction model. Hosmer-Lemeshow test was used to determine the goodness of fit of the model. The receiver operator characteristic curve （ROC） was used to test the prediction effect of the model,and a nomogram model was drawn. 60 children with congenital heart disease after surgery in the same hospital from December 2021 to February 2022 were selected as the validation group,and Hosmer-Lemeshow test and ROC curve were used for external verification of the model. Results The incidence of CADVT in children with congenital heart disease after surgery was 22.65%. Intubation duration（OR=1.172）,D-dimer concentration（OR=1.169）,fibrinogen concentration（OR=3.888）,days of sedation（OR=1.538）,using of vasoconstrictor（OR=3.554） and pediatric critical illness score（OR=3.308） were its risk factors（P<0.05）. The Hosmer-Lemeshow test showed that χ²=4.456,P=0.814,the area under the ROC curve was 0.957（95%CI：0.930~0.984）,the optimal critical value was 0.813,the sensitivity was 0.962,and the specificity was 0.851. In the external validation,the sensitivity,specificity and accuracy of the model were 0.857,0.870,86.67%,respectively. Conclusion The risk prediction model constructed in this study has good effects,which can provide a reference for clinical evaluation of the risk of CADVT in children with congenital heart disease after surgery.